The Obelisk of Urbino is one of twelve original Egyptian obelisks in Italy. It was brought to Rome around 90 AD, when it was located in the Egyptian city of Sais. It was demolished under Emperor Theodosius I, following the abolition of pagan cults.

Urbino Cathedral is a Catholic cathedral dedicated to the Assumption of the Blessed Virgin Mary. The first cathedral on the site was built here in 1021, to replace an earlier one located outside the city walls. Under the patronage of Count Federico da Montefeltro, it was rebuilt in the 15th century, based on a design attributed to Francesco di Giorgio Martini. Construction was not finished until 1604.