Ladenburg's history goes back to the Celtic (3000 BC) and Roman Ages, when it was called Lopodunum. Emperor Trajan elevated it to city status ('civitas') in 98 AD. It was a central trading town and one of the most important Roman cities in Southwestern Germany.

The historic old town and its Fachwerkhäuser date back to the Late Middle Ages when Ladenburg was the capital of the Prince-Bishopric of Worms. Ladenburg is considered being the oldest town in Germany on the right bank of the river Rhine.

Nowadays Ladenburg’s historic old town speaks for itself with medieval town fortifications, picturesque half-timbered houses and casy alleys and squares.

Ladenburg is part of the Deutsche Fachwerkstraße(Timber-Frame Road)), connecting towns with timber framed buildings.