Larissa Castle (Κάστρο Λάρισα) - the ancient and medieval acropolis of the city of Argos - is located on the top of the Larissa hill on a height of 289 meters above the city of Argos. The first inhabitants of the area were the Pelasgians - pre-Hellenic people inhabiting parts of Greece - and the names "Argos" and "Larissa" are pelasgian. The meaning of the first was “valley” and of the latter “acropolis”.

Τhe castle was created in the 6th century B.C. but there was a fortification there since prehistoric times and the epoch of the Pelasgians. The medieval castle was first built by the Byzantines in the 10th century. During the Byzantine period, the fortress was of strategic importance. In 1203, it came under the control of the archon of Nafplio. In 1212 it was captured by Othon de la Roche, the Bourgoundian Duke of Athens, and was controlled by the Franks until 1388.

Between 1394 and 1463 it was occupied by the Venetians. In 1463 it was captured by the Turks and remained under their control until 1822, interrupted during 1686-1715, when Larissa came under the control of the Venetians. The site was liberated by the Greeks in 1822 during the Greek War of Independence. .