From the beginning until the 10th century the region of Arta belonged to the Metropolis of Corinth and later to the Metropolis of Nicopolis. After the destruction of Nikopolis (11th century) the whole area of Epirus was subordinated to the Metropolis of Nafpaktos. Arta became the seat of a bishopric in the 12th century.

The Metropolitan Church of St. Demetrios is located in the center of Arta.